Applied Evidence Research Institute

Applied Evidence Research InstituteApplied Evidence Research InstituteApplied Evidence Research Institute

Applied Evidence Research Institute

Applied Evidence Research InstituteApplied Evidence Research InstituteApplied Evidence Research Institute
  • Home
  • About Us
    • About
    • ConcoursCorrect
    • FASTR
    • ASCEND
  • AERI Data Lab
  • AERI Insights
    • Thought Leadership
    • Partner Advocacy Orgs
    • Publications
  • More
    • Home
    • About Us
      • About
      • ConcoursCorrect
      • FASTR
      • ASCEND
    • AERI Data Lab
    • AERI Insights
      • Thought Leadership
      • Partner Advocacy Orgs
      • Publications
  • Home
  • About Us
    • About
    • ConcoursCorrect
    • FASTR
    • ASCEND
  • AERI Data Lab
  • AERI Insights
    • Thought Leadership
    • Partner Advocacy Orgs
    • Publications

AERI Data Lab

AERI Data Lab

The AERI Data Lab is the analytic and informatics hub of the Applied Evidence Research Institute, purpose-built to advance real-world evidence generation in complex clinical domains. We specialize in structuring and interrogating high-dimensional health data to uncover signals that can improve diagnosis, treatment, and patient outcomes.

Housed within a nonprofit research environment, the Data Lab supports AERI's three strategic verticals:


  1. ConcoursCorrect: Investigating the real-world epidemiology and patient-level predictors of immune-related adverse events (irAEs) in cancer immunotherapy.
  2. FASTR: Illuminating diagnostic delays and missed signals in rare and underrecognized diseases, leveraging longitudinal data to inform earlier detection.
  3. AERI Insights: Providing analytic rigor to the public education and advocacy outputs that define AERI’s knowledge translation and policy work.


Capabilities

  • Real-World Data Curation: We work with EHR, claims, registry, and patient-reported data sources to build analyzable cohorts reflecting the complexity of clinical care.
  • Phenotype Development: Using rule-based and machine learning methods, we create robust computable phenotypes for conditions, events, and treatment patterns.
  • Signal Detection: Our team applies statistical, causal inference, and time-series techniques to identify associations and trajectories often obscured in unstructured or noisy data.
  • Data Ethics & Governance: Every project is grounded in rigorous data stewardship, with attention to IRB standards, patient privacy, and responsible use.


Collaborative Model

The AERI Data Lab operates on a collaborative research model. We partner with academic investigators, clinical centers, advocacy organizations, and health systems to:

  • Jointly design and execute studies that require complex data analytics
  • Support grant development and data strategy for funded research
  • Translate findings into actionable tools, publications, and educational resources



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